Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293) 质控信息
Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293) 生物活性
描述
Butyrophilin 2A2 (BTN2A2) is a widely expressed type I transmembrane glycoprotein that functions as a negative regulator of immune responses. Mature human Butyrophilin 2A2 consisits of a 233 amino acid (aa) extracellular domain with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 237 aa cytoplasmic domain. Alternative splicing generates additional isoforms of human Butyrophilin 2A2 that lack the first, second, or both Iglike domains as well as isoforms with substitutions and deletions in the cytoplasmic region. Within the immune system, Butyrophilin 2A2 is expressed on thymic epithelial cells, naïve B cells, splenic NK cells, dendritic cells, and peritoneal macrophages and is up-regulated with cell activation. Butyrophilin 2A2 inhibits T cell proliferation and activation and enhances the development of FoxP3+ regulatory T cells. Its up-regulation in the hippocampus is associated with schizophrenia.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293) 技术信息
CAS号
N/A
分子量
49.7 KDa
SMILES Code
NONE
别名
重组人BTN2A2蛋白(C-Fc, HEK293)
;Recombinant Human BTN2A2 (C-Fc, HEK293); Butyrophilin subfamily 2 member A2; BTN2A2
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293)
|Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293)
| 重组人BTN2A2蛋白(C-Fc, HEK293)
| Recombinant Human BTN2A2 (C-Fc, HEK293)
| Butyrophilin subfamily 2 member A2
| BTN2A2
| N/A
| Butyrophilins
| Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293) 纯度/质量文件
| Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293) 生物活性
| Human BTN2A2 (C-Fc, HEK293)/人BTN2A2蛋白(C-Fc, HEK293) 技术信息
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