货号:A2924174
同义名:
重组人BTC蛋白(C-Flag-Fc, HEK293)
/ Recombinant Human BTC (C-Flag-Fc, HEK293); BTC
Recombinant Human BTC (C-Flag-Fc, HEK293) 是人源Betacellulin蛋白,在HEK293人源细胞中表达,带有C端Flag-Fc标签。该蛋白属于EGF家族,具有六个半胱氨酸形成的三对二硫键,可结合并激活ErbB-1和ErbB-4受体,参与调控胰腺β细胞分化及胃肠生长,对多种细胞类型具有促有丝分裂活性,广泛应用于细胞信号与肿瘤研究。


| 规格 | 价格 | 会员价 | 库存 | 数量 | |||
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| 描述 | Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Betacellulin is characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family. Betacellulin is expressed in several tissues and tumor cells including kidney, uterus, liver, pancreas and small intestine. Betacellulin binds and activates ErbB-1 and ErbB-4 homodimers. Betacellulin is thought to play a role in the differentiation of pancreatic beta cells.Human and mouse mature BTC protein are 80% identical at the amino acid sequence level. Betacellulin is involved in many biological processes such as stimulating gastrointestinal growth. It is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen for a wide variety of cell types. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-Flag-Fc |
| 蛋白表达区间 | Asp32-Tyr111 |
| 蛋白编号 | P35070 |
| 内毒素 | < 0.01 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 34.5 KDa |
| SMILES Code | NONE |
| 别名 | 重组人BTC蛋白(C-Flag-Fc, HEK293) ;Recombinant Human BTC (C-Flag-Fc, HEK293); BTC; Betacellulin |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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