货号:A2960913
同义名:
Apoptotic protease-activating factor 1
Human APAF1是来自智人(人)的蛋白,在酵母中表达,带有N端6xHis标签。该寡聚蛋白介导细胞色素c依赖性的前半胱天冬酶-9(Apaf - 3)的自催化激活,从而导致半胱天冬酶-3的激活和细胞凋亡,这一激活过程需要ATP。亚型6在诱导细胞凋亡方面效果较差。


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| 描述 | Human APAF1是来自智人(人)的蛋白,在酵母中表达,带有N端6xHis标签。该寡聚蛋白介导细胞色素c依赖性的前半胱天冬酶-9(Apaf - 3)的自催化激活,从而导致半胱天冬酶-3的激活和细胞凋亡,这一激活过程需要ATP。亚型6在诱导细胞凋亡方面效果较差。 |
| 蛋白种属 | Human |
| 表达系统 | Yeast |
| 标签 | N-6His |
| 蛋白表达区间 | 104-415aa,Partial |
| 蛋白编号 | O14727 |
| 氨基酸序列 | SGITSYVRTV LCEGGVPQRP VVFVTRKKLV NAIQQKLSKL KGEPGWVTIH GMAGCGKSVL AAEAVRDHSL LEGCFPGGVH WVSVGKQDKS GLLMKLQNLC TRLDQDESFS QRLPLNIEEA KDRLRILMLR KHPRSLLILD DVWDSWVLKA FDSQCQILLT TRDKSVTDSV MGPKYVVPVE SSLGKEKGLE ILSLFVNMKK ADLPEQAHSI IKECKGSPLV VSLIGALLRD FPNRWEYYLK QLQNKQFKRI RKSSSYDYEA LDEAMSISVE MLREDIKDYY TDLSILQKDV KVPTKVLCIL WDMETEEVED IL |
| 剂型 | 干粉 |
| 剂型描述 | The buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week. |
| CAS号 | N/A |
| 分子量 | 37.4 kDa |
| SMILES Code | NONE |
| 别名 | Apoptotic protease-activating factor 1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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