Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293)
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货号：A2925393同义名：
重组人ANGPTL4蛋白(N-6His, HEK293)
/ Recombinant Human ANGPTL4 (N-6His, HEK293); Angiopoietin-related protein 4
Recombinant Human ANGPTL4 (N-6His, HEK293)是人源蛋白，在HEK293细胞中表达，带有N端6×His标签。该蛋白为分泌型，含1个纤维蛋白原C端结构域，可调节血管生成与肿瘤发生，抑制内皮细胞增殖、迁移及管腔形成，减少血管渗漏，参与调控糖稳态、脂代谢及胰岛素敏感性，在缺氧条件下可抑制内皮细胞黏附与迁移。
Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 化学结构 CAS号：N/A
Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 3D分子结构 CAS号：N/A
Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 质控信息
Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 生物活性
描述
Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, pH7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 技术信息
CAS号
N/A
分子量
27.9 KDa
SMILES Code
NONE
别名
重组人ANGPTL4蛋白(N-6His, HEK293)
;Recombinant Human ANGPTL4 (N-6His, HEK293); Angiopoietin-related protein 4; 425O18-1; Angiopoietin-like protein 4; Fasting-induced adipose factor; Hepatic fibrinogen/angiopoietin-related protein; HFARP; Secreted protein Bk89; Angptl4; Farp; Fiaf; Ng27
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293)
|Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293)
| 重组人ANGPTL4蛋白(N-6His, HEK293)
| Recombinant Human ANGPTL4 (N-6His, HEK293)
| Angiopoietin-related protein 4
| 425O18-1
| Angiopoietin-like protein 4
| Fasting-induced adipose factor
| Hepatic fibrinogen/angiopoietin-related protein
| HFARP
| Secreted protein Bk89
| Angptl4
| Farp
| Fiaf
| Ng27
| N/A
| Angiopoietins
| Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 纯度/质量文件
| Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 生物活性
| Human ANGPTL4 (N-6His, HEK293)/人ANGPTL4蛋白(N-6His, HEK293) 技术信息
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