货号:A2925595
同义名:
重组人ANG1蛋白(N-Fc, HEK293)
/ Recombinant Human ANG1 (N-Fc, HEK293); AGP1
Recombinant Human ANG1 (N-Fc, HEK293)是人类血管生成素1蛋白,在人源细胞中表达,带有N端Fc标签。该蛋白在血管发育与维持中起关键作用,是TIE2信号通路的重要激活因子,能够保护肺动脉高压,减轻糖尿病心肌梗死后的纤维化与重构,并可能促进肿瘤进展与转移。


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| 描述 | Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | N-Fc |
| 蛋白表达区间 | Asp256-Phe498 |
| 蛋白编号 | Q15389 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 53.9 KDa |
| SMILES Code | NONE |
| 别名 | 重组人ANG1蛋白(N-Fc, HEK293) ;Recombinant Human ANG1 (N-Fc, HEK293); AGP1; AGPT; Ang1; ANG-1; angiopoietin 1; Angiopoietin-1; ANGPT1 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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