Recombinant HIV gp120 (C-8His, HEK293)是来自HIV的包膜糖蛋白gp120，在HEK293人源细胞中表达，带有C端8个组氨酸标签。该蛋白为Env三聚体中非共价结合的gp120-gp41异二聚体之一，经切割后形成成熟糖蛋白，与gp41共同构成病毒表面的刺突结构。其包含一段17个氨基酸的免疫抑制区，相关合成肽段可体外及体内抑制免疫功能。
HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 化学结构 CAS号：N/A
HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 3D分子结构 CAS号：N/A
HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 质控信息
HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 生物活性
描述
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 技术信息
CAS号
N/A
分子量
57 KDa
SMILES Code
NONE
别名
重组HIV gp120蛋白(C-8His, HEK293)
;Recombinant HIV gp120 (C-8His, HEK293); Envelope glycoprotein gp120; Glycoprotein 120; Surface protein gp120
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293)
|HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293)
| 重组HIV gp120蛋白(C-8His, HEK293)
| Recombinant HIV gp120 (C-8His, HEK293)
| Envelope glycoprotein gp120
| Glycoprotein 120
| Surface protein gp120
| N/A
| HIV Proteins
| HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 纯度/质量文件
| HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 生物活性
| HIV gp120 (C-8His, HEK293)/HIV gp120蛋白(C-8His, HEK293) 技术信息
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