货号:A680549
同义名:
Gastrin I (human);Gastrin Heptadecapeptide I (human)
Gastrin I, human是一种内源性胃肠肽激素,可以与胆囊收缩素(CCK)受体结合。
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描述 | The peptide cholecystokinin (CCK), originally discovered in the gastrointestinal tract, has been shown to mediate pancreatic secretion and contraction of gallbladder. Two types of CCK receptors (CCK1 found in the gut and CCK2 found in the brain) have thus been distinguished. Gastrin-1, human, a endogenous peptide produced in the stomach, increases gastric acid secretion via acting at CCK2 receptor[1]. In anaesthetized rats, gastrin-1, human (1.5, 5, 15 and 45 nmol/kg, i.v.) increased both pepsinogen and acid secretion. After pretreatment with omeprazole, gastrin-1, human failed to stimulate acid secretion, while it increased pepsinogen output. In rats with gastric perfusion of acid solutions, gastrin-1, human increased peptic output in a pH-independent manner either with or without pretreatment with omeprazole[2]. |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
0.48mL 0.10mL 0.05mL |
2.38mL 0.48mL 0.24mL |
4.77mL 0.95mL 0.48mL |
CAS号 | 10047-33-3 |
分子式 | C97H124N20O31S |
分子量 | 2098.203 |
别名 | Gastrin I (human);Gastrin Heptadecapeptide I (human);Gastrin I (1-17) (human) |
运输 | 蓝冰 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
溶解方案 |
DMSO: 50 mg/mL(23.83 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO NH4OH: 50 mg/mL(23.83 mM),配合低频超声,并调节pH至11 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
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动物实验配方 |