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Fumagillin/烟曲霉素
Fumagillin/烟曲霉素
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货号：A859732
同义名：
Amebacilin; NSC9168
Fumagillin 是一种抗菌剂，可通过抑制 HIV-1 viral protein R 活性来抑制 HIV‐1 感染。
Fumagillin/烟曲霉素 化学结构
Fumagillin/烟曲霉素 3D分子结构
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Fumagillin/烟曲霉素 纯度/质量文件 产品仅供科研
货号：A859732
标准纯度：
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全球学术期刊中引用的产品
• Science , 2025, 387(6729): eadp5637. Ambeed. • Nat. Electron. , 2025, 8, 66-74. Ambeed. • Adv. Mater. , 2025, 2416621. Ambeed. • Adv. Mater. , 2025, 2410493. Ambeed. • Adv. Mater. , 2025, 2420319. Ambeed. A106129
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Fumagillin/烟曲霉素 质控信息
Fumagillin/烟曲霉素 生物活性
描述
Fumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus[3] [4] [5] [6]
Fumagillin/烟曲霉素 参考文献
[1] Watanabe N, Nishihara Y, et al. Fumagillin suppresses HIV-1 infection of macrophages through the inhibition of Vpr activity. FEBS Lett. 2006 May 15;580(11):2598-602.
[2] Sin N, Meng L, Wang MQ, et al. The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6099-103.
[3] Lefkove B, Govindarajan B, Arbiser JL. Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors. Expert Rev Anti Infect Ther. 2007 Aug;5(4):573-9
[4] An J, Wang L, Patnode ML, Ridaura VK, Haldeman JM, Stevens RD, Ilkayeva O, Bain JR, Muehlbauer MJ, Glynn EL, Thomas S, Muoio D, Summers SA, Vath JE, Hughes TE, Gordon JI, Newgard CB. Physiological mechanisms of sustained fumagillin-induced weight loss. JCI Insight. 2018 Mar 8;3(5):e99453
[5] Guruceaga X, Perez-Cuesta U, Pellon A, Cendon-Sanchez S, Pelegri-Martinez E, Gonzalez O, Hernando FL, Mayayo E, Anguita J, Alonso RM, Keller NP, Ramirez-Garcia A, Rementeria A. Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage. J Fungi (Basel). 2021 Nov 3;7(11):936
[6] Zbidah M, Lupescu A, Jilani K, Lang F. Stimulation of suicidal erythrocyte death by fumagillin. Basic Clin Pharmacol Toxicol. 2013 May;112(5):346-51
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Fumagillin/烟曲霉素 实验方案
计算器
摩尔计算器
总药量计算器
工作液计算器
存储液制备
1mg
5mg
10mg
1 mM
5 mM
10 mM
2.18mL
0.44mL
0.22mL
10.90mL
2.18mL
1.09mL
21.81mL
4.36mL
2.18mL
Fumagillin/烟曲霉素 技术信息
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