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/ Dehydroacetic acid/脱氢乙酸

Dehydroacetic acid/脱氢乙酸 {[allProObj[0].p_purity_real_show]}

货号：A177106 同义名： Biocide 470F; Methylacetopyronone

Dehydroacetic acid是一种吡喃酮衍生物，作为杀菌剂、杀菌剂或食品防腐剂使用。

Dehydroacetic acid/脱氢乙酸 化学结构 CAS号：520-45-6
Dehydroacetic acid/脱氢乙酸 化学结构
CAS号：520-45-6
Dehydroacetic acid/脱氢乙酸 3D分子结构
CAS号：520-45-6
Dehydroacetic acid/脱氢乙酸 化学结构 CAS号：520-45-6
Dehydroacetic acid/脱氢乙酸 3D分子结构 CAS号：520-45-6
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Dehydroacetic acid/脱氢乙酸 纯度/质量文件 产品仅供科研

货号：A177106 标准纯度： {[allProObj[0].p_purity_real_show]}
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Dehydroacetic acid/脱氢乙酸 生物活性

描述 Dehydroacetic acid is a common pyrone derivative used commercially as an antibacterial and antifungal agent. Based on the synthesis of dehydroacetic acid from N-hydroxysuccinimdyl acetoacetate, a novel series of enamine-based derivatives were synthesised in order to improve the antibacterial activity of dehydroacetic acid[3]. Analogues of dehydroacetic acid as selective and potent agonists of an ectopic odorant receptor through a combination of hydrophilic and hydrophobic interactions[4]. Moreover, dehydroacetic acid was effective both in controlling growth and guaiacol formation by A. acidoterrestris. Through the addition of 270 mg/L dehydroacetic acid, the A. acidoterrestris counts were reduced by 3.43 log colony forming unit (CFU)/mL, and no guaiacol was detected after 14 days of storage[5].

Dehydroacetic acid/脱氢乙酸 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02177383 Oxidative Stress ... 展开 >> Exercise Training Season Antioxidant Capabilities Athletic Performance 收起 << Not Applicable Completed - Spain ... 展开 >> University of Balearic Islands Palma de Mallorca, Balearic Islands, Spain, 07122 收起 <<

Dehydroacetic acid/脱氢乙酸 参考文献

[1]Manku GS, Sarpal PD. Dehydroacetic acid as a reagent for the separation and gravimetric determination of copper(II), aluminium and beryllium. Talanta. 1971 Oct;18(10):1079-82.

[2]Ukita T, Ejima A. [Mode of antibacterial activity of 3-acetyl-4-hydroxycoumarin and dehydroacetic acid. I] . Yakugaku Zasshi. 1962 Dec;82:1625-30. Japanese.

[3]Baldwin AG, Bevan J, Brough D, Ledder R, Freeman S. Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid. Med Chem Res. 2018;27(3):884-889. doi: 10.1007/s00044-017-2110-8.

[4]Park BB, Lee N, Kim Y, Jae Y, Choi S, Kang N, Hong YR, Ok K, Cho J, Jeon YH, Lee EH, Byun Y, Koo J. Analogues of Dehydroacetic Acid as Selective and Potent Agonists of an Ectopic Odorant Receptor through a Combination of Hydrophilic and Hydrophobic Interactions. ChemMedChem. 2017 Apr 6;12(7):477-482.

[5]Cai R, Yuan Y, Wang Z, Guo C, Liu B, Pan C, Liu L, Yue T. Effects of preservatives on Alicyclobacillus acidoterrestris growth and guaiacol production. Int J Food Microbiol. 2015 Dec 2;214:145-150.

Dehydroacetic acid/脱氢乙酸 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

5.95mL

1.19mL

0.59mL

29.74mL

5.95mL

2.97mL

59.47mL

11.89mL

5.95mL

Dehydroacetic acid/脱氢乙酸 技术信息

CAS号520-45-6
分子式C8H8O4
分子量 168.15
SMILES Code CC(C1C(C=C(C)OC1=O)=O)=O
MDL No. MFCD00066709
别名 Biocide 470F; Methylacetopyronone; NSC 139150
运输蓝冰
InChI Key PGRHXDWITVMQBC-UHFFFAOYSA-N
Pubchem ID 122903
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry,2-8°C
溶解方案

DMSO: 50 mg/mL(297.36 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

Tags: Dehydroacetic acid | 520-45-6 | Biocide 470F | Bacterial Inhibitor | Anti-infection | Bacterial | Fungal | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | Dehydroacetic acid/脱氢乙酸 纯度/质量文件 | Dehydroacetic acid/脱氢乙酸 生物活性 | Dehydroacetic acid/脱氢乙酸 临床数据 | Dehydroacetic acid/脱氢乙酸 参考文献 | Dehydroacetic acid/脱氢乙酸 实验方案 | Dehydroacetic acid/脱氢乙酸 技术信息

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