There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type
HazMat fee for 500 gram (Estimated)
Excepted Quantity
USD 0.00
Limited Quantity
USD 15-60
Inaccessible (Haz class 6.1), Domestic
USD 80+
Inaccessible (Haz class 6.1), International
USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic
USD 100+
Accessible (Haz class 3, 4, 5 or 8), International
Chlorohexidine is cationic bis-biguanide broad spectrum antiseptic with both anti-plaque and antibacterial properties[3]. Topical application of chlorohexidine resulted in a marked reduction of plaque formation, substantial improvement in gingival condition, and considerable decrease in the germ content of the plaque. A significant reduction in oral germ count could be determined in the experimental animals. However, it was not possible to observe a significant inhibition of caries production[4]. Combined use of fluorides and chlorohexidine was seen to exert an inhibitory action on the progress of dental caries[5]. Chlorehexidine (0.2%) and a phenolic mouth rinse significantly reduced plaque growth and gingival inflammation compared to a placebo mouthrinse, however chlorhexidine rinse was more effective against plaque regrowth than the phenolic rinse[6].
Chlorhexidine/氯己定 细胞实验
Cell Line
Concentration
Treated Time
Description
References
Acinetobacter baumannii
8 µM
30 min
To investigate the role of AceR in regulating aceI gene expression under chlorhexidine induction. Results showed that chlorhexidine induced a 34-fold increase in aceI gene expression in the WT strain, while this induction was abolished in the DaceR mutant strain.
J Antimicrob Chemother. 2018 Jun 1;73(6):1492-1500.
Chlorhexidine/氯己定 动物实验
Species
Animal Model
Administration
Dosage
Frequency
Description
References
Mice
Partial ischemia-reperfusion injury model
Topical disinfection
0.5% in 70% Ethanol
Single use
Used for topical disinfection before surgery
Nat Commun. 2023 Jul 21;14(1):4407
C57BL/6J mice
Ecological Time-Sequential Polybacterial Periodontal Infection (ETSPPI) model
Oral rinse
0.12%
Once on day 5
Suppress existing oral bacteria and facilitate subsequent bacterial colonization
Int J Mol Sci. 2022 May 4;23(9):5107
Mice
Pain model
Intrathecal injection
0.025 to 0.75 mg/kg
Single injection, lasting 4 hours
To evaluate the analgesic effect of Consomatin Ro1, results showed dose-dependent antinociception when injected intraperitoneally but no significant effect when injected intrathecally.
Korea, Republic of
... 展开 >>
Seoul National University Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Jee Youn Moon, M.D. 82-10-5299-2036 jymoon0901@gmail.com
Principal Investigator: Jee Youn Moon, M.D. 收起 <<
Korea, Republic of
... 展开 >>
Seoul National University Hospital
Recruiting
Seoul, Korea, Republic of
Contact: Jee Youn Moon, M.D. 82-10-5299-2036 jymoon0901@gmail.com
Principal Investigator: Jee Youn Moon, M.D. 收起 <<
A Known Allergy to Antiseptic ... 展开 >>Soap
Women Who Had Any Infection in the Perioperative Period
A Known Allergy to Chlorohexidine Alcohol or Shellfis 收起 <<
United States, New York
... 展开 >>
New York Presbyterian Hospital at Columbia University and Children's Hospital of New York
Recruiting
New York, New York, United States, 10032
Contact: Cassandra R. Duffy, MD 929-286-0292 crd2130@columbia.edu 收起 <<
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