货号:A2925736
同义名:
重组生物素化人VCAM-1蛋白(C-Avi-6His, HEK293)
/ Biotinylated Human VCAM-1 (C-Avi-6His, HEK293); Vascular cell adhesion protein 1
Biotinylated Human VCAM-1 (C-Avi-6His, HEK293) 是人源VCAM-1蛋白,在HEK293人源细胞中表达,带有C端Avi及6His标签。该蛋白又称CD106或INCAM-110,属于免疫球蛋白超家族,是一种重要的细胞黏附分子,主要介导白细胞与内皮细胞的黏附,通过与白细胞表面的整合素α4β1(ITGA4/ITGB1)相互作用,参与免疫应答及炎症部位的白细胞迁移。


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| 描述 | VCAM-1 (CD106, INCAM-110) is a cell adhesion molecule and a member of the immunoglobulin superfamily. It's important function is a recognition of cell-cell. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation。 |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-Avi-6His |
| 蛋白表达区间 | Phe25-Glu698 |
| 蛋白编号 | P19320 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 76.9 KDa |
| SMILES Code | NONE |
| 别名 | 重组生物素化人VCAM-1蛋白(C-Avi-6His, HEK293) ;Biotinylated Human VCAM-1 (C-Avi-6His, HEK293); Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; CD106; INCAM-100 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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