/Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351)
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351)
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货号：A2926617同义名：
重组生物素化人Nectin-4蛋白(C-6His-Avi, HEK293)(Gly32-Val351)
/ Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351); PVRL4
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)是人源蛋白，在HEK293人源细胞中表达，带有C端6His-Avi标签。该产品为Nectin-4（PVRL4）的一部分，包含两个Ig样C2型结构域和一个Ig样V型结构域，主要参与细胞间粘附，通过与同源及异源分子（如Nectin-1）相互作用发挥作用。该蛋白在胎盘、胚胎及乳腺癌组织中高表达，其可溶性形式可能通过ADAM17介导的蛋白水解产生。
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 化学结构 CAS号：N/A
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 3D分子结构 CAS号：N/A
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 质控信息
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 生物活性
描述
Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 技术信息
CAS号
N/A
分子量
37.2 KDa
SMILES Code
NONE
别名
重组生物素化人Nectin-4蛋白(C-6His-Avi, HEK293)(Gly32-Val351)
;Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351); PVRL4; Nectin-4; Ig superfamily receptor LNIR; Poliovirus receptor-related protein 4; PRR4; LNIR
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351)
|Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351)
| 重组生物素化人Nectin-4蛋白(C-6His-Avi, HEK293)(Gly32-Val351)
| PVRL4
| Nectin-4
| Ig superfamily receptor LNIR
| Poliovirus receptor-related protein 4
| PRR4
| LNIR
| N/A
| Cell Adhesion Molecules (CAMs)
| Nectin-4/Recombinant Protein
| Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 纯度/质量文件
| Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 生物活性
| Biotinylated Human Nectin-4 (C-6His-Avi, HEK293)(Gly32-Val351) 技术信息
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