Biotinylated Human Mucin-1(C-Fc-Avi, HEK293)
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货号：A2925598同义名：
重组生物素化人Mucin-1蛋白(C-Fc-Avi, HEK293)
/ Biotinylated Human Mucin-1(C-Fc-Avi, HEK293); Mucin-1
Biotinylated Human Mucin-1(C-Fc-Avi, HEK293)是人源Mucin-1蛋白，在HEK293细胞中表达，带有C-Fc-Avi标签。该蛋白是膜结合型粘蛋白家族成员，主要表达于肺、乳腺、胃和胰腺等组织上皮细胞的顶端膜，具有保护黏膜屏障、调控信号通路及影响肿瘤进展的作用，同时具备黏附与抗黏附双重功能。
Biotinylated Human Mucin-1(C-Fc-Avi, HEK293) 化学结构 CAS号：N/A
Biotinylated Human Mucin-1(C-Fc-Avi, HEK293) 3D分子结构 CAS号：N/A
Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells. MUC-1 can act both as an adhesion and an anti-adhesion protein. This protein may provide a protective layer on epithelial cells against bacterial and enzyme attack. MUC-1 participated in modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, MUC-1 influences directly or indirectly the Ras/MAPK pathway. MUC-1 promotes tumor progression and regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Biotinylated Human Mucin-1(C-Fc-Avi, HEK293) 技术信息
CAS号
N/A
分子量
44 KDa
SMILES Code
NONE
别名
重组生物素化人Mucin-1蛋白(C-Fc-Avi, HEK293)
;Biotinylated Human Mucin-1(C-Fc-Avi, HEK293); Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD227; MUC1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Biotinylated Human Mucin-1(C-Fc-Avi, HEK293)
|Biotinylated Human Mucin-1(C-Fc-Avi, HEK293)
| 重组生物素化人Mucin-1蛋白(C-Fc-Avi, HEK293)
| Mucin-1
| MUC-1
| Breast carcinoma-associated antigen DF3
| Cancer antigen 15-3
| CA 15-3
| Carcinoma-associated mucin
| Episialin
| H23AG
| Krebs von den Lungen-6
| KL-6
| PEMT
| Peanut-reactive urinary mucin
| PUM
| Polymorphic epithelial mucin
| PEM
| Tumor-associated epithelial membrane antigen
| EMA
| Tumor-associated mucin
| CD227
| MUC1
| N/A
| Epithelial cell CD Proteins
| MUC-1/CD227
| Biotinylated Human Mucin-1(C-Fc-Avi, HEK293) 纯度/质量文件
| Biotinylated Human Mucin-1(C-Fc-Avi, HEK293) 生物活性
| Biotinylated Human Mucin-1(C-Fc-Avi, HEK293) 技术信息
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