Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293)
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货号：A2925693同义名：
重组生物素化人IgG1 Fc蛋白(C-Avi, HEK293)
/ Biotinylated Human IgG1 Fc (C-Avi, HEK293); g gamma-1 chain C region
Biotinylated Human IgG1 Fc (C-Avi, HEK293) 是人源 IgG1 Fc 片段蛋白，在 HEK293 人源细胞中表达，带有 C-Avi 标签。该蛋白是免疫球蛋白 G1 的 Fc 段，主要参与机体二次免疫应答，是唯一能穿过胎盘的抗体类型，具有抗原结合、补体激活、毒素中和及 ADCC 等功能，常用于免疫检测与抗体研发。
Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 化学结构 CAS号：N/A
Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 3D分子结构 CAS号：N/A
Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 质控信息
Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 生物活性
描述
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 技术信息
CAS号
N/A
分子量
27.7 KDa
SMILES Code
NONE
别名
重组生物素化人IgG1 Fc蛋白(C-Avi, HEK293)
;Biotinylated Human IgG1 Fc (C-Avi, HEK293); g gamma-1 chain C region; IGHG1
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293)
|Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293)
| 重组生物素化人IgG1 Fc蛋白(C-Avi, HEK293)
| Biotinylated Human IgG1 Fc (C-Avi, HEK293)
| g gamma-1 chain C region
| IGHG1
| N/A
| Immunoglobulin Fc Region
| Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 纯度/质量文件
| Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 生物活性
| Biotinylated Human IgG1 Fc (C-Avi, HEK293)/生物素化人IgG1 Fc蛋白(C-Avi, HEK293) 技术信息
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