/Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293)
Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293)
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货号：A2925735同义名：
重组生物素化人IL-17RA蛋白(C-Fc, HEK293)
/ Biotinylated Human IL-17RA (C-Fc, HEK293); Interleukin-17 receptor A
Biotinylated Human IL-17RA (C-Fc, HEK293)是人源蛋白，在HEK293人源细胞中表达，带有C-Fc标签。该产品为白细胞介素17A受体，属于I型膜糖蛋白，可低亲和力结合促炎细胞因子IL-17A，后者由活化的T淋巴细胞分泌并参与诱导中性粒细胞成熟。IL-17A及其受体在类风湿性关节炎等炎症与自身免疫疾病中发挥致病作用，该受体可能具有多聚体结构。
Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293) 化学结构 CAS号：N/A
Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293) 3D分子结构 CAS号：N/A
Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293) 质控信息
Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293) 生物活性
描述
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Biotinylated Human IL-17RA (C-Fc, HEK293)/生物素化人IL-17RA蛋白(C-Fc, HEK293) 技术信息
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