Biotinylated Human GPC3 (C-6His-Avi, HEK293)
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货号：A2925474同义名：
重组生物素化人GPC3蛋白(C-6His-Avi, HEK293)
/ Biotinylated Human GPC3 (C-6His-Avi, HEK293); Glypican-3
Biotinylated Human GPC3 (C-6His-Avi, HEK293)是人源蛋白，在HEK293细胞中表达，带有C端6His-Avi标签。该蛋白属于糖磷脂酰肌醇锚定蛋白家族，高表达于肺、肝和肾，是一种硫酸乙酰肝素蛋白聚糖，在肝癌、恶性黑色素瘤等多种肿瘤中过表达，与细胞生长分化相关，是肝癌的可靠标志物，可作为肿瘤标志物及免疫治疗潜在靶点。
Biotinylated Human GPC3 (C-6His-Avi, HEK293) 化学结构 CAS号：N/A
Biotinylated Human GPC3 (C-6His-Avi, HEK293) 3D分子结构 CAS号：N/A
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms such as hepatocellular carcinoma, malignant melanoma, and testicular yolk sac tumor, and plays an important role in cell growth and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a tumor suppressor gene, whereas in others, it acts as an oncofetal protein. GPC3 is a reliable marker for hepatocellular carcinoma. The sensitivity and specificity exceeds both alpha-fetoprotein and hepatocyte-paraffin1. GPC3 immunohistochemistry can aid in the differentiation of testicular germ cell tumors, being expressed in all yolk sac tumors but not in seminomas. GPC3 expression has also been identified in some squamous cell carcinomas of the lung and clear cell carcinomas of the ovary. Glypican-3 is currently regarded as a tumor marker and potential target for immunotherapy.
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存，建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释，如果是做无血清培养或者动物体内实验时，细胞因子中不能含有BSA、FBS 和 HAS，可以使用海藻糖作为载体，然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子，并避免反复冻融；稀释分装浓度不低于 10μg/mL，分装体积不低于10μL。
分装后的蛋白在≤-20°C 下可稳定保存 3 个月。
Biotinylated Human GPC3 (C-6His-Avi, HEK293) 技术信息
CAS号
N/A
分子量
63.4 KDa
SMILES Code
NONE
别名
重组生物素化人GPC3蛋白(C-6His-Avi, HEK293)
;Biotinylated Human GPC3 (C-6His-Avi, HEK293); Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7; GPC3; OCI5
运输
蓝冰
存储条件
In solvent-20°C:3-6个月-80°C:12个月
Pure formSealed in dry, store in freezer, under -20°C
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Tags:
Biotinylated Human GPC3 (C-6His-Avi, HEK293)
|Biotinylated Human GPC3 (C-6His-Avi, HEK293)
| 重组生物素化人GPC3蛋白(C-6His-Avi, HEK293)
| Glypican-3
| GTR2-2
| Intestinal protein OCI-5
| MXR7
| GPC3
| OCI5
| N/A
| GPC-3
| Biotinylated Human GPC3 (C-6His-Avi, HEK293) 纯度/质量文件
| Biotinylated Human GPC3 (C-6His-Avi, HEK293) 生物活性
| Biotinylated Human GPC3 (C-6His-Avi, HEK293) 技术信息
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