货号:A2925577
同义名:
重组生物素化人CD79B蛋白(C-6His-Avi, HEK293)
/ Biotinylated Human CD79B (C-6His-Avi, HEK293); B-Cell Antigen Receptor Complex-Associated Protein Beta Chain
Biotinylated Human CD79B (C-6His-Avi, HEK293) 是人源CD79B蛋白,在HEK293细胞中表达,带有C端6×His和Avi标签。该蛋白为单次跨膜I型膜蛋白,含一个Ig样V型结构域和一个ITAM结构域,与CD79A协同启动B细胞抗原受体复合物(BCR)信号转导级联,促进复合物内化、转运至晚期内体并参与抗原呈递,同时增强CD79A磷酸化。


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| 描述 | CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His-Avi |
| 蛋白表达区间 | Ala29-Asp159 |
| 蛋白编号 | P40259 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 18.1 KDa |
| SMILES Code | NONE |
| 别名 | 重组生物素化人CD79B蛋白(C-6His-Avi, HEK293) ;Biotinylated Human CD79B (C-6His-Avi, HEK293); B-Cell Antigen Receptor Complex-Associated Protein Beta Chain; B-Cell-Specific Glycoprotein B29; Ig-Beta; Immunoglobulin-Associated B29 Protein; CD79b; CD79B; B29; IGB |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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