货号:A2925658
同义名:
重组生物素化人BTN3A2蛋白(C-6His-Avi, HEK293)
/ Biotinylated Human BTN3A2 (C-6His-Avi, HEK293); Butyrophilin subfamily 3 member A2
Biotinylated Human BTN3A2 (C-6His-Avi, HEK293)是人源BTN3A2蛋白,在HEK293人源细胞中表达,带有C端6×His和Avi标签,简称为Biotinylated Human BTN3A2。该蛋白属于BTN家族和Ig超家族,是单次跨膜Ⅰ型膜蛋白,成熟形式含305个氨基酸,具免疫相关表达特性,可调节T细胞应答,抑制IFN-γ释放,在适应性免疫中发挥作用。


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| 描述 | Butyrophilin subfamily 3 member A2, also known as BT3.2, BTF3, BTF4 and BTN3A2, is a single-pass type I membrane protein. It is a member of the butyrophilin (BTN) family and the immunoglobulin (IG) superfamily. Mature human BTN3A2 is a 305 amino acid (aa) glycoprotein. It contains a 219 aa extracellular region with one V-type Ig-like domain, and a 65 aa cytoplasmic tail. The cytoplasmic region undergoes phosphorylation on two serines. There are three potential splice forms. BTN3A2 is postulated to be expressed on immune-related cells, as it has a structural similarity to MHC and CD80/CD86 molecules. It plays a role in T-cell responses in the adaptive immune response and inhibits the release of IFNG from activated T-cells. |
| 蛋白种属 | Human |
| 表达系统 | Human Cells |
| 标签 | C-6His-Avi |
| 蛋白表达区间 | Gln30-Trp248 |
| 蛋白编号 | P78410 |
| 内毒素 | < 1 EU/µg as determined by LAL test. |
| 剂型 | 干粉 |
| 剂型描述 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.如要长期保存,建议使用含载体蛋白(如 0.1%BSA、10%FBS、5%HSA)的溶液进一步稀释,如果是做无血清培养或者动物体内实验时,细胞因子中不能含有BSA、FBS 和 HAS,可以使用海藻糖作为载体,然后分装冻存于-20℃至-80℃。注:分装保存时建议使用低吸附的管子,并避免反复冻融;稀释分装浓度不低于 10μg/mL,分装体积不低于10μL。 分装后的蛋白在≤-20°C 下可稳定保存 3 个月。 |
| CAS号 | N/A |
| 分子量 | 26.5 KDa |
| SMILES Code | NONE |
| 别名 | 重组生物素化人BTN3A2蛋白(C-6His-Avi, HEK293) ;Biotinylated Human BTN3A2 (C-6His-Avi, HEK293); Butyrophilin subfamily 3 member A2; BT3.2; BTF3; BTF4; BTN3A2 |
| 运输 | 蓝冰 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, store in freezer, under -20°C |
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