Betulonic acid, a natural product isolated and purified from the branch of Eucalyptus globulus Labill., belongs to the pentacyclic triterpenic derivative class, has antitumor activities.
Betulonic acid, a natural product isolated and purified from the branch of Eucalyptus globulus Labill., belongs to the pentacyclic triterpenic derivative class, has antitumor activities.
Betulonic acid/路路通酸 细胞实验
Cell Line
Concentration
Treated Time
Description
References
Primary porcine alveolar macrophages (PAMs)
5.4 µM
24 h
To evaluate the inhibitory effect of BA on PRRSV replication in PAMs, results showed BA significantly inhibited PRRSV replication
Int J Mol Sci. 2024 Sep 26;25(19):10366
Marc-145 cells
3.3 µM to 3.7 µM
48 h
To evaluate the inhibitory effect of BA on PRRSV replication, results showed BA significantly inhibited PRRSV replication
Int J Mol Sci. 2024 Sep 26;25(19):10366
GES-1 cells
20, 40, 80, 160 µM
24, 48, 72 h
To evaluate the effect of Betulonic acid on the viability of GES-1 cells, the results showed that GES-1 cells were less sensitive to Betulonic acid than AGS and HGC-27 cells.
Molecules. 2022 Feb 2;27(3):1025
HGC-27 cells
20, 40, 80, 160 µM
24, 48, 72 h
To evaluate the effect of Betulonic acid on the viability of HGC-27 cells, the results showed that Betulonic acid inhibited the viability of HGC-27 cells in a concentration- and time-dependent manner.
Molecules. 2022 Feb 2;27(3):1025
AGS cells
20, 40, 80, 160 µM
24, 48, 72 h
To evaluate the effect of Betulonic acid on the viability of AGS cells, the results showed that Betulonic acid inhibited the viability of AGS cells in a concentration- and time-dependent manner.
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