货号:A142721
同义名:
抗坏血酸棕榈酸酯
/ L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid
Ascorbyl palmitate是由抗坏血酸与棕榈酸形成的酯,创造出一种脂溶性的维生素 C,亦作为抗氧化剂食品添加剂使用。


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| 描述 | Ascorbyl palmitate (AP) is a fatty acid ester endowed with antioxidant properties, used as a food additive and cosmetic ingredient, which is presently produced by chemical synthesis[3]. Ascorbyl palmitate can interact with amylose to form amylose-lipid complexes. About 93% and 66% of ascorbyl palmitate were encapsulated when 15mg and 50mg was respectively added to maize starch during pasting[4]. The growth of HUVECs (Human Umbilical Vein Endothelial Cells)was decreased upon treatment with AP in dose-and time-dependent manner. Furthermore, real time PCR results showed that AP induces apoptosis by up-regulation of caspase-3, 9 and down-regulation of Bcl-2 ratio[5]. Ascorbyl palmitate (AP) and sodium ascorbyl phosphate (SAP) supplementations to skin proved a promising choice for controlling facial sebum secretions and could be evaluated for undesired oily skin and acne reductions for beautifying the facial appearance[6]. |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01066182 | Learning Beha... 展开 >>viour 收起 << | Phase 2 | Completed | - | United Kingdom ... 展开 >> Department of Social Policy and Social Work Oxford, Oxfordshire, United Kingdom, OX1 2ER 收起 << |
| NCT03201588 | Ophthalmological Disorder | Not Applicable | Recruiting | December 31, 2019 | Sweden ... 展开 >> Queen Silvias Childrens Hospital Recruiting Göteborg, Sweden, 41650 Contact: Karin Savman, MD,PhD +46 ext 739940937 karin.savman@vgregion.se Contact: Svetlana Najm, MD +46 ext 738999992 svatlana.najm@vgregion.se Skanes Universitetssjukhus Recruiting Lund, Sweden Contact: David Ley, Professor +46 ext 709264824 david.ley@med.lu.se Contact: Ingrid Pupp, MD,PhD +46 ext 761712021 ingrid.pupp@med.lu.se KI Recruiting Stockholm, Sweden, 14157 Contact: Boubou Hallberg, MD.PhD +46 ext 700021010 boubou.hallberg@karolinska.se Contact: Dirk Wackernagel, MD +46 ext 700011758 dirk.wackernagel@karolinska.se 收起 << |
| NCT01192269 | Healthy | Not Applicable | Completed | - | Germany ... 展开 >> Ludwig Maximilians University Munich, Germany, 80337 收起 << |
| 计算器 | ||||
| 存储液制备 | ![]() |
1mg | 5mg | 10mg |
|
1 mM 5 mM 10 mM |
2.41mL 0.48mL 0.24mL |
12.06mL 2.41mL 1.21mL |
24.12mL 4.82mL 2.41mL |
|
| CAS号 | 137-66-6 |
| 分子式 | C22H38O7 |
| 分子量 | 414.53 |
| SMILES Code | OC([C@H](O1)[C@H](COC(CCCCCCCCCCCCCCC)=O)O)=C(O)C1=O |
| MDL No. | MFCD00005377 |
| 别名 | 抗坏血酸棕榈酸酯 ;L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid; HSDB 418; CCRIS 3930; BRN 0096552; 6-Palmitoylascorbic acid; Vitamin C palmitate; NSC 402451; Ascorbylpalmitic Acid |
| 运输 | 蓝冰 |
| InChI Key | QAQJMLQRFWZOBN-LAUBAEHRSA-N |
| Pubchem ID | 54680660 |
| 存储条件 |
In solvent -20°C: 3-6个月 -80°C: 12个月 Pure form Sealed in dry, room temperature |
| 溶解方案 |
DMSO: 105 mg/mL(253.3 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO 以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
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