There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.
Type | HazMat fee for 500 gram (Estimated) |
Excepted Quantity | USD 0.00 |
Limited Quantity | USD 15-60 |
Inaccessible (Haz class 6.1), Domestic | USD 80+ |
Inaccessible (Haz class 6.1), International | USD 150+ |
Accessible (Haz class 3, 4, 5 or 8), Domestic | USD 100+ |
Accessible (Haz class 3, 4, 5 or 8), International | USD 200+ |
规格 | 价格 | 会员价 | 库存 | 数量 | |||
---|---|---|---|---|---|---|---|
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快速发货 顺丰冷链运输,1-2 天到达
品质保证
技术支持
免费溶解
描述 | Abacavir is a competitive nucleoside reverse transcriptase inhibitor with oral activity. It inhibits HIV replication and displays anticancer potential in prostate cancer cell lines. Additionally, Abacavir can cross the blood-brain barrier and inhibit telomerase activity[1].[2].[3]. |
体内研究 | Furthermore, Abacavir (50 mg/kg/d, administered intraperitoneally for 14 days) in combination with 0.1 mg/kg/d Decitabine enhances survival in mice bearing high-risk medulloblastoma[3]. |
体外研究 | At concentrations of 15 and 150 μM over 0-120 hours, Abacavir suppresses cell growth, affects cell cycle progression, induces senescence, and modulates LINE-1 mRNA expression in prostate cancer cell lines[1]. Also, at the concentration of 15 and 150 μM, Abacavir significantly reduces cell migration and invasion at after 18 hours[1]. |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
NCT02868580 | Amyotrophic Lateral Sclerosis | Phase 2 | Active, not recruiting | June 2018 | Australia, New South Wales ... 展开 >> Macquarie Neurology North Ryde, New South Wales, Australia, 2109 Westmead Hospital Parramatta, New South Wales, Australia, 2150 Brain and Mind Centre Sydney, New South Wales, Australia, 2050 Australia, Victoria Calvary Health Care Bethlehem Caulfield South, Victoria, Australia, 3162 收起 << |
NCT00085943 | HIV Infection ... 展开 >> Infection, Human Immunodeficiency Virus 收起 << | Phase 3 | Completed | - | - |
NCT00005017 | HIV Infections | Phase 4 | Unknown | - | United States, North Carolina ... 展开 >> Jaime Hernandez Research Triangle Park, North Carolina, United States, 27709 收起 << |
计算器 | ||||
存储液制备 | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
3.49mL 0.70mL 0.35mL |
17.46mL 3.49mL 1.75mL |
34.92mL 6.98mL 3.49mL |
CAS号 | 136470-78-5 |
分子式 | C14H18N6O |
分子量 | 286.33 |
SMILES Code | OC[C@@H]1C=C[C@H](N2C=NC3=C(NC4CC4)N=C(N)N=C23)C1 |
MDL No. | MFCD00903850 |
别名 | 1592U89 |
运输 | 蓝冰 |
InChI Key | MCGSCOLBFJQGHM-SCZZXKLOSA-N |
Pubchem ID | 441300 |
存储条件 |
In solvent -20°C:3-6个月-80°C:12个月 Pure form Sealed in dry, room temperature |
溶解方案 |
DMSO: 105 mg/mL(366.71 mM),配合低频超声助溶,注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO H2O: 2 mg/mL(6.98 mM),配合低频超声助溶 |