MLKL

货号		产品名	纯度
A1191953	现货	(E/Z)-Necrosulfonamide Necrosulfonamide is a necroptosis inhibitor by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3).	≥98%
A157358	现货	TC13172 TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2±0.6 nM for HT-29 cells.	≥98%
A1176842	现货	GW806742X GW806742X, an ATP analog, is a potent MLKL inhibitor that binds to the MLKL pseudokinase domain with a Kd value of 9.3μM. GW806742X has anti-VEGFR2 activity (IC50=2 nM). GW806742X delays MLKL membrane displacement and inhibits necrosis.	≥99%
A750842	现货	Necrosulfonamide Necrosulfonamide is a necroptosis inhibitor that selectively targets the mixed lineage kinase domain-like protein (MLKL), preventing the MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during necrosis induction.	≥99%

货号

产品名

纯度

A1191953

现货

Necrosulfonamide is a necroptosis inhibitor by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3).

≥98%

A157358

现货

TC13172

TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2±0.6 nM for HT-29 cells.

≥98%

A1176842

现货

GW806742X

GW806742X, an ATP analog, is a potent MLKL inhibitor that binds to the MLKL pseudokinase domain with a Kd value of 9.3μM. GW806742X has anti-VEGFR2 activity (IC50=2 nM). GW806742X delays MLKL membrane displacement and inhibits necrosis.

≥99%

A750842

现货

Necrosulfonamide

Necrosulfonamide is a necroptosis inhibitor that selectively targets the mixed lineage kinase domain-like protein (MLKL), preventing the MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during necrosis induction.

≥99%