Ambeed.cn

首页 / / / LRRK2

货号 产品名 纯度
A206371 现货 GNE0877

GNE0877 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor with an IC50 of 3 nM.

99%+
A1601847 现货 EB-42486

EB-42486 是一种新型、高选择性的G2019S-LRRK2抑制剂,IC50 < 0.2 nM。

99%+
A269266 现货 CZC-25146

CZC-25146 is a potent LRRK2 inhibitor with IC50 values of 4.76 and 6.87 nM for for wild-type and G2019S mutant LRRK2, respectively. It also inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2.

99%+
A1177088 现货 PFE-360

PFE-360是一种选择性的 LRRK2 抑制剂,能够有效透过血脑屏障,对神经退行性疾病具有潜在的研究价值。

98%
A1500046 现货 CZC-54252 HCl

CZC-54252 HCl是一种选择性的 LRRK2 抑制剂,显示出对 G2019S LRRK2 突变体的神经保护作用,广泛用于神经退行性疾病(如帕金森病)的研究。

99%+
A142087 现货 GSK2578215A

GSK2578215A is a brain-penetrant, potent and selective LRRK2 inhibitor with IC50 values of 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2, respectively.

99%+
A408166 现货 CZC-54252

CZC-54252 is a potent LRRK2 inhibitor with IC50 values of 1.28 nM and 1.85 nM for wild-type and G2019S mutant LRRK2, respecitively, possessing neuroprotective effect.

99%+
A303998 现货 MLi-2

MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity.

99%+
A210153 现货 GNE-7915

GNE-7915是一种高度选择性和能穿透血脑屏障的LRRK2抑制剂,其IC50值为9 nM。

99%+
A281167 现货 LRRK2-IN-1

LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 values of 6 and 13 nM for G2019S mutant and wild-type LRRK2, respectively.

99%+
A369305 现货 GNE-9605

GNE-9605 is a selective and potent LRRK2 with IC50 value of 18.7 nM.

99%+
A248253 现货 JH-II-127

JH-II-127 is a brain-penetrant, potent and selective LRRK2 inhibitor with IC50 values of 2.2, 6.6 and 47.7 nM for G2019S-mutant, wild-type and A2016T-mutant LRRK2, respectively.

98%+
A125109 现货 PF-06447475

PF-06447475 is a brain-penetrant, potent and selective LRRK2 inhibitor with IC50 values of 3 nM, possessing neuroprotective activity.

99%+
A930369 现货 IKK 16

IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.

98%
A1680467 GSK2646264

98%
A1467726 PF-06371900

PF-06371900 is a selective LRRK2 inhibitor with IC50 value of 64nM.

A2288218 LRRK2-IN-6

98%
A1810532 LRRK2-IN-7

98%
A1717527 PF-06455943

98%
A2791628 PF-06447475

99+%
产品名 LRRK2 其他靶点 纯度
GNE-7915 ++++

LRRK2, IC50: 9 nM

LRRK2, Ki: 1 nM

99%+
GNE-9605 +++

LRRK2, IC50: 19 nM

LRRK2, Ki: 2 nM

99%+
GSK2578215A ++

LRRK2 (G2019S), IC50: 8.9 nM

LRRK2 (WT), IC50: 10.9 nM

99%+
URMC-099 +

LRRK2, IC50: 11 nM

99%+
PF-06447475 +++

LRRK2, IC50: 3nM

99%+
LRRK2-IN-1 ++

LRRK2 (G2019S), IC50: 6 nM

LRRK2 (WT), IC50: 13 nM

99%+
GNE0877 ++++

LRRK2, Ki: 0.7 nM

99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
Ambeed 相关网站 Ambeed.cn Ambeed.com
Ambeed
关于我们
联系我们
资讯中心
网站地图
产品手册
  • 批次文件查询
  • 客户支持
    技术支持
    专业术语
    缩略词释义
    质量手册
    产品咨询
    计算器
    活动政策
    订购方法
    积分商城
    活动声明
    联系我们
    400-920-2911 sales@ambeed.cn tech@ambeed.cn
    Ambeed 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务,不为任何个人或者非科研性质用途提供服务。