Jatrophane 2
                                    
                                        
                                            Jatrophane 2, a natural product isolated and purified from the branches of Jatropha carcas L., exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera), and demonstrates the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR).