MK886 is an inhibitor of 5-lipoxygenase activating protein (FLAP), PPARα, and the biosynthesis of leukotriene (LT).

Diflapolin is a dual inhibitor of both FLAP and sEH. It inhibited 5-LOX product formation in intact human monocytes and neutrophils with IC50 = 30 and 170 nM, respectively, and suppressed the activity of isolated sEH (IC50 = 20 nM).

AZD5718 is a novel Inhibitor of 5-Lipoxygenase Activating Protein(FLAP).

Masoprocol is an antineoplastic drug used to treat skin growths caused by sun exposure. A form of nordihydroguaiaretic acid that is taken by mouth is being studied in the treatment of prostate cancer.

AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.

Veliflapon is a potent inhibitor of 5-lipoxygenase activating protein (FLAP).

GSK2190915 is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM.

MK591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor.

GSK2190915 sodium salt is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM.

MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay.