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货号 产品名 纯度
A326728 KJ Pyr 9

KJ Pyr 9 is a small-molecule inhibitor of MYC. The Kd of KJ Pyr 9 for MYC in vitro is 6.5±1.0 nM, as determined by backscattering interferometry.

99%+
A1251864 MYCi361

MYCi361 is a MYC inhibitor with Kd value of 3.2μM. It engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy.

99%+
A561489 10074-A4

95%
A385405 ML327

ML327 is a blocker of MYC which can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).

99%+
A708851 Mycro 3

Mycro3 is a small-molecule inhibitor of Myc-Max dimerization. The average residual tumor of Pdx1-cre/KRAS* mice after Mycro3 treatment (100mg/kg, orally, daily for 2 months) is approximately 30%.

99%+
A1329217 MYCMI-6

MYCMI-6 (NSC354961) is a potent and selective endogenous MYC:MAX protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC50<0.5 μM). MYCMI-6 is not cytotoxic to normal human cells. MYCMI-6 induces apoptosis .

99%+
A1060062 EN4

95%
A1251865 MYCi975

MYCi975 improved analog of MYCi361 which is a MYC inhibitor. It showed better tolerability compared with MYCi361.

99%+
A1176708 IZCZ-3

IZCZ-3 是一种有效的 c-MYC 转录抑制剂,具有抗肿瘤活性。

95%
A1371160 Agrimol B/仙鹤草酚 B

Agrimol B 是一种多酚类化合物,口服有效的 SIRT1 激活剂。它具有抗脂肪生成和抗癌活性,并对植物病原体表现出抗菌特性。

99%+
A2666914 10058-F4

99%+
A1601128 c-Myc inhibitor 4

98%
A2420047 c-Myc inhibitor 12

98%
A1678243 Anticancer agent 84

98%
A188479 10074-G5

10074-G5 is a c-Myc Max interaction inhibitor.

99%+
A382705 Secalonic acid D

97%
A1549492 VPC-70619

98%
A2419947 c-Myc inhibitor 11

98%
A1544125 hnRNPK-IN-1

98%
A1951062 WBC100

98%
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