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首页 / 蛋白降解靶向嵌合体 / PROTAC功能分子 / Bromodomain BET/PROTAC

货号 产品名 纯度
A475199 现货 dBET6

dBET6是一种高效、选择性和细胞可渗透的PROTAC,靶向Cereblon和BETIC50为14 nM,表现出抗肿瘤活性。

99%+
A1546984 现货 SJ995973

95%
A290656 现货 dBET1

dBET1 is a PROTAC, consisting of a BRD4-ligand JQ-1 linkerd to a cereblon E3 ligase ligand, targeting on BET bromodomain BRD4

99%+
A176193 现货 dBET57

dBET57 is a BRD4 heterobifunctional small-molecule ligand (PROTAC), exhibits significant and selective degradation of BRD4 BD1 (DC50/5h=500 nM), but is inactive on BRD4 BD2.

99%+
A1147982 现货 A1874

A1874 is a nutlin-based PROTAC targeting on BRD4, consist of a BRD4-ligand JQ1 linked to a MDM2 E3 ligase ligand RG7388.

99%+
A365449 现货 ARV-771

ARV-771 is a PROTAC targeting on pan-BET, containing a BRD4-binding moiety (JQ-1) and a VHL-binding moiety.

97%
A482817 PROTAC BET Degrader 9

PROTAC BET degrader-9 is PROTAC targeting on BET proteins, consist of a BET inhibitor HJB97 as the warhead ligand and Pomalidomide as CRBN ligand.

98%
A887929 BETd-260

PROTAC BET Degrader 23 is a highly potent and efficacious PROTAC targeting on BET with DC50 value of 30pM for degradation of BRD4 in RS4;11 leukemia cell line.

98%
A1365406 RC32

98+%
A1251853 FKBP12 PROTAC dTAG-7

98%
A1177249 LY 254155

99+%
A1549609 Proguanil-d4 HCl

98% +98%atom%D
A1148116 PROTAC BRD9 Degrader-1

PROTAC BRD9 Degrader-1 is a PROTAC targeting on BRD9, consist of a BRD9 bromodomain probe I-BRD9 as a warhead ligand and pomalidomide as the CRBN ligand.

99%
A749396 BETd-246

BETd-246 is a second-generation BET bromodomain inhibitor. It causes a dose-dependent depletion of BRD2, BRD3 and BRD4 in representative TNBC cell lines with 30-100 nM for 1 h or with 10-30 nM for 3 h incubation.

98%
A563444 QCA570

QCA570 is a potent PROTAC targeting on BET, consist of an optimized BET ligand QCA276 linked to a CRBN E3 ligand.

99%
A1548983 OARV-771

98%
A1553454 (S)-GNE-987

98%
A1148016 PROTAC BET degrader-2

PROTAC BET degrader-25 is PROTAC targeting on BET proteins, consist of a BET inhibitor HJB97 as the warhead ligand and a Lenalidomide analogue as the CRBN ligand.

98%
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