1-Palmitoyl-sn-glycero-3-phosphocholine

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Chemical Structure| 17364-16-8 同义名 : lyso-PPC; 1-Palmitoyl-sn-glycero-3-phosphorylcholine
CAS号 : 17364-16-8
货号 : A865426
分子式 : C24H50NO7P
纯度 : 99%+
分子量 : 495.63
MDL号 : MFCD00036904
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

H2O: 50 mg/mL(100.88 mM)，配合低频超声助溶
生物活性
描述 1-Palmitoyl-sn-glycero-3-phosphocholine, a prevalent lysophosphatidylcholine, displays proinflammatory effects. It is utilized in researching atherosclerosis[1][2][3][4].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.02mL

0.40mL

0.20mL

10.09mL

2.02mL

1.01mL

20.18mL

4.04mL

2.02mL
参考文献

[1]Choi S, et al. Superoxide generated by lysophosphatidylcholine induces endothelial nitric oxide synthase downregulation in human endothelial cells. Cell Physiol Biochem. 2010;25(2-3):233-40.

[2]Qin X, et al. Lysophosphatidylcholine perpetuates macrophage polarization toward classically activated phenotype in inflammation. Cell Immunol. 2014 May-Jun;289(1-2):185-90.

[3]Hasegawa H, et al. Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β production. Biochem Biophys Res Commun. 2011 Nov 25;415(3):526-31.

[4]Yan JJ, et al. Therapeutic effects of lysophosphatidylcholine in experimental sepsis. Nat Med. 2004 Feb;10(2):161-7.