Corynoline

产品说明书

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Chemical Structure| 18797-79-0 同义名 : 紫堇灵 ;13-methyl-Chelidonine; CRL; FT0688360; PL002006; BT000613; (d)-Corynoline; (+)-Corynoline
CAS号 : 18797-79-0
货号 : A837021
分子式 : C21H21NO5
纯度 : 99%
分子量 : 367.4
MDL号 : MFCD11042250
存储条件：

Pure form Sealed in dry,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 40 mg/mL(108.87 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 (+)-Corynoline, a natural product isolated and purified from the tubers of Corydalis ambigua, is an acetylcholinesterase inhibitor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.72mL

0.54mL

0.27mL

13.61mL

2.72mL

1.36mL

27.22mL

5.44mL

2.72mL
参考文献

[1]Mao X, Peng Y, Zheng J. In Vitro and In Vivo Characterization of Reactive Intermediates of Corynoline. Drug Metab Dispos. 2015 Oct;43(10):1491-8.

[2]Naruto S, Arakawa S, Kaneko H. Conformational analysis of corynoline and its related compounds. Tetrahedron Lett. 1968 Feb;14:1705-9.