Evenamide
产品说明书
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同义名 : | NW-3509 |
| CAS号 : | 1092977-61-1 | |
| 货号 : | A748019 | |
| 分子式 : | C16H26N2O2 | |
| 纯度 : | 97% | |
| 分子量 : | 278.39 | |
| MDL号 : | MFCD28502433 | |
| 存储条件： |
Pure form Sealed in dry,Store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 105 mg/mL(377.17 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Evenamide (NW-3509) emerges as an orally active blocker of voltage-gated sodium channels (VGSCs), with a Ki of 0.4 µM, tailored for schizophrenia research. Its effectiveness spans across a wide array of rodent models for psychosis, mania, depression, and aggressiveness[1].[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.59mL 0.72mL 0.36mL |
17.96mL 3.59mL 1.80mL |
35.92mL 7.18mL 3.59mL |
| 参考文献 |
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