Monensin Sodium Salt
产品说明书
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同义名 : | Monensin A sodium; Monensin A; NSC 343257; Sodium Monensin; Monensin sodium |
| CAS号 : | 22373-78-0 | |
| 货号 : | A735800 | |
| 分子式 : | C36H61NaO11 | |
| 纯度 : | 98% +(A+B);≥800ug/mg | |
| 分子量 : | 692.85 | |
| MDL号 : | MFCD26960926 | |
| 存储条件： |
Pure form Inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 2 mg/mL(2.89 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO 无水乙醇: 20 mg/mL(28.87 mM)，配合低频超声助溶，注意：无水乙醇开封后，易挥发，也会吸收空气中的水分，导致溶解能力下降，请避免使用开封较久的乙醇 |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Monensin sodium, an orally administered antibiotic, operates as an ionophore that facilitates Na+/H+ exchange and is recognized as a potent inhibitor of Wnt signaling. It causes a noticeable enlargement of multivesicular bodies (MVBs) and influences the regulation of exosome secretion. Monensin sodium is applied in research related to bacterial, fungal, and parasitic infections and exhibits anticancer efficacy[1][2][3][4]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01576770 | Pain on Propofol IV Injection | Phase 4 | Unknown | January 2013 | United States, Texas ... 展开 >> Memorial Herman Hospital Recruiting Houston, Texas, United States, 77030 收起 << |
| NCT01096589 | - | Completed | - | - | |
| NCT02728986 | Varicose Ulcer | Not Applicable | Unknown | December 2017 | France ... 展开 >> Quimper Center Recruiting Quimper, France Contact: P, MD 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
1.44mL 0.29mL 0.14mL |
7.22mL 1.44mL 0.72mL |
14.43mL 2.89mL 1.44mL |
| 参考文献 |
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