Pocapavir
产品说明书
 |
同义名 : | SCH-48973; V-073; V074 |
| CAS号 : | 146949-21-5 | |
| 货号 : | A724355 | |
| 分子式 : | C21H17Cl3O3 | |
| 纯度 : | 99%+ | |
| 分子量 : | 423.72 | |
| MDL号 : | MFCD00950032 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 105 mg/mL(247.81 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Pocapavir, also known as SCH-48973, is an orally active capsid inhibitor. Pocapavir prevents viruses from entering cells and then unencapsulating them. Pocapavir has antiviral activity against poliovirus and also inhibits enteroviral infections[1].Pocapavir belongs to a group of picornavirus antiviral mechanisms that prevent viral replication by preventing viral uncoating and release of viral RNA into cells[2]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.36mL 0.47mL 0.24mL |
11.80mL 2.36mL 1.18mL |
23.60mL 4.72mL 2.36mL |
