Fasudil
产品说明书
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同义名 : | AT877; HA-1077 |
| CAS号 : | 103745-39-7 | |
| 货号 : | A702414 | |
| 分子式 : | C14H17N3O2S | |
| 纯度 : | 95% | |
| 分子量 : | 291.37 | |
| MDL号 : | MFCD00866182 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Fasudil hydrochloride is a potent inhibitor of ROCK-II, PKA, PKG, PKC, and MLCK with Ki of 0.33 μM, 1.6 μM, 1.6 μM, 3.3 μM and 36 μM, respectively. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT01069042 | Heart Failure | Phase 4 | Unknown | November 2010 | Taiwan ... 展开 >> National Cheng Kung University Hospital Recruiting Tainan, Taiwan, 70401 Contact: Ping-Yen Liu, MD, PhD 收起 << |
| NCT03404843 | Cardiovascular Diseases | Phase 2 | Completed | - | United States, Colorado ... 展开 >> Colorado State University, Dept. of Health and Exercise Science Fort Collins, Colorado, United States, 80523 收起 << |
| NCT01823081 | Diabetic Macular Edema | Phase 3 | Completed | - | Iran, Islamic Republic of ... 展开 >> Tehran, Iran, Islamic Republic of 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
3.43mL 0.69mL 0.34mL |
17.16mL 3.43mL 1.72mL |
34.32mL 6.86mL 3.43mL |
| 参考文献 |
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