Verbenalin

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Chemical Structure| 548-37-8 同义名 : Cornin; NSC 118055; Verbenalol glucoside; Verbenalol β-D-glucopyranoside
CAS号 : 548-37-8
货号 : A655719
分子式 : C17H24O10
纯度 : 99%+
分子量 : 388.37
MDL号 : MFCD27996262
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(270.36 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Cornin, a natural product isolated and purified from the fruits of Cornus officinalis Sieb. et Zucc.,induces angiogenesis in vitro via a programmed PI3K/Akt/eNOS/VEGF signaling axis and has protective potential against cerebral ischemia injury and its protective effects may be due to amelioration of cerebral mitochondrial function and its antioxidant property.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.57mL

0.51mL

0.26mL

12.87mL

2.57mL

1.29mL

25.75mL

5.15mL

2.57mL
参考文献

[1]Kang Z, Jiang W, et al. Cornin induces angiogenesis through PI3K-Akt-eNOS-VEGF signaling pathway. Food Chem Toxicol. 2013 Aug;58:340-6.

[2]Jiang WL, Zhang SP, et al. Cornin ameliorates cerebral infarction in rats by antioxidant action and stabilization of mitochondrial function. Phytother Res. 2010 Apr;24(4):547-52.