Atosiban acetate

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Chemical Structure| 914453-95-5 同义名 : RW22164 acetate; RWJ22164 acetate; Atosiban(acetate)
CAS号 : 914453-95-5
货号 : A601702
分子式 : C45H71N11O14S2
纯度 : 98+%
分子量 : 1054.24
MDL号 : -
存储条件：

Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(99.6 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 50 mg/mL(47.43 mM)，配合低频超声助溶
生物活性
描述 Atosiban acetate (also known as RW22164 acetate or RWJ22164 acetate), a nonapeptide, functions as a competitive antagonist to vasopressin/oxytocin receptors and is an analog of desamino-oxytocin. It is primarily used as a tocolytic agent for the investigation of spontaneous preterm labor[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

0.95mL

0.19mL

0.09mL

4.74mL

0.95mL

0.47mL

9.49mL

1.90mL

0.95mL
参考文献

[1]Sanu O, et al. Critical appraisal and clinical utility of atosiban in the management of preterm labor. Ther Clin Risk Manag. 2010 Apr 26;6:191-9.

[2]Philip J Ryan, et al. Oxytocin-receptor-expressing Neurons in the Parabrachial Nucleus Regulate Fluid Intake. Nat Neurosci. 2017 Dec;20(12):1722-1733.