Tamarixetin

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Chemical Structure| 603-61-2 同义名 : 4'-O-Methyl Quercetin; 4'-methoxy Quercetin
CAS号 : 603-61-2
货号 : A601013
分子式 : C16H12O7
纯度 : 98+%
分子量 : 316.26
MDL号 : MFCD00017308
存储条件：

Pure form Keep in dark place,Inert atmosphere,2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 50 mg/mL(158.1 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Tamarixetin, a natural product isolated and purified from the herbs of Heracleum stenopterum with potential protective effect against cancer and cardiovascular diseases, can inhibit proliferation in a concentration- and time-dependent manner, induce apoptosis and block cell cycle progression at G2 -M phase.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.16mL

0.63mL

0.32mL

15.81mL

3.16mL

1.58mL

31.62mL

6.32mL

3.16mL
参考文献

[1]Nicolini F, Burmistrova O, et al. Induction of G2/M phase arrest and apoptosis by the flavonoid tamarixetin on human leukemia cells. Mol Carcinog. 2014 Dec;53(12):939-50.

[2]Moalin M, van Strijdonck GP, et al. Competition between ascorbate and glutathione for the oxidized form of methylated quercetin metabolites and analogues: tamarixetin, 4'O-methylquercetin, has the lowest thiol reactivity. J Agric Food Chem. 2012 Sep 12;60(36):9292-7.