Amenamevir
产品说明书
 |
同义名 : | ASP 2151 |
| CAS号 : | 841301-32-4 | |
| 货号 : | A588976 | |
| 分子式 : | C24H26N4O5S | |
| 纯度 : | 99%+ | |
| 分子量 : | 482.55 | |
| MDL号 : | MFCD19443709 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : |
DMSO: 50 mg/mL(103.62 mM)，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Amenamevir (ASP2151) inhibits the replication of HSV strains isolated from Japan, the United States, and laboratory-stocked strains. The EC50s of Amenamevir against HSV-1 and HSV-2 are significantly lower than those of acyclovir (ACV) [1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.07mL 0.41mL 0.21mL |
10.36mL 2.07mL 1.04mL |
20.72mL 4.14mL 2.07mL |
| 参考文献 |
|---|
|
[1]Cho JW, et al. Isoxazole derivatives and use thereof. WO2007078113A1. |