Furosemide

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Chemical Structure| 54-31-9 同义名 : 呋喃苯胺酸;利尿磺胺;速尿;速尿灵 ;Frusemide; NSC 269420
CAS号 : 54-31-9
货号 : A406627
分子式 : C12H11ClN2O5S
纯度 : 98%
分子量 : 330.74
MDL号 : MFCD00010549
存储条件:

Pure form Keep in dark place, inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 :

DMSO: 105 mg/mL(317.47 mM),注意:DMSO长时间开封后,会吸水并导致溶解能力下降,请避免使用长期开封的DMSO

动物实验配方:
生物活性
描述 Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.02mL

0.60mL

0.30mL

15.12mL

3.02mL

1.51mL

30.24mL

6.05mL

3.02mL

参考文献

[1]Gutschmidt KU, Stenkamp K, et al. Anticonvulsant actions of furosemide in vitro. Neuroscience. 1999;91(4):1471-81.

[2]Charak BS, Louie R, et al. The effect of amphotericin B, aztreonam, imipenem and cephalosporins on the bone marrow progenitor cell activity. J Antimicrob Chemother. 1991 Jan;27(1):95-104.