| 生物活性 | |||
|---|---|---|---|
| 描述 | Immunoglobulin heavy constant epsilon is knowed as Immunoglobulin (Ig) E, which causes the immediate allergic reaction, is produced by B lymphocytes through the class switching. Constant region of membrane-bound IgE (long mIgE), part of the B cell receptor complex (BCR). Upon antigen cross-linking triggers quick BCR signaling, ensuring survival of IgE-switched B cells and differentiation into plasma cells, thus regulating both primary and memory IgE responses. | ||