Human IL-2 R beta&IL-2 R gamma Heterodimer Protein (C-Fc, HEK293)
产品说明书
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同义名 : | 重组人IL-2 R beta&IL-2 R gamma异二聚体蛋白(C-Fc&C-Fc, HEK293) ;Recombinant Human IL-2 R beta&IL-2 R gamma Heterodimer Protein (C-Fc, HEK293); IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG |
| CAS号 : | N/A | |
| 货号 : | A2926443 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 54&51 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
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| 描述 | The interleukin 2 (IL-2) receptor (IL-2R) is a multisubunit receptor that includes three major IL-2 binding subunits, the IL-2R alpha, beta, and gamma chains. We have detected and analyzed cooperative interactions between the IL-2R alpha and beta chains (IL-2R alpha and IL-2R beta, respectively) in COS cells transfected with cDNAs encoding the IL-2R alpha, the IL-2R beta, or both cDNAs.The affinities of Neo-2/15 for the human and mouse IL-2 receptors (IL-2Rβ and IL-2Rβγc) are significantly higher than those of the corresponding native IL-2 cytokines. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. | ||