E.coli Trp synthase (N-6His, E.coli)

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Chemical Structure| N/A 同义名 : 重组大肠杆菌Trp synthase蛋白(N-6His, E.coli) ;Recombinant E.coli Trp synthase (N-6His, E.coli); Tryptophan synthetase; Tryptophan synthase
CAS号 : N/A
货号 : A2926177
分子式 : -
纯度 : 95% determined by reducing SDS-PAGE.
分子量 : 28.7&43.8 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -70°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 Tryptophan synthase is a multienzyme α2β2 complex composed of two protein subunit. Tryptophan synthase catalyzes the last two steps in the synthesis of L-tryptophan (L-Trp). The α-subunit catalyzes cleavage of 3-indole-d-glycerol 3′-phosphate (IGP) to give indole and D-glyceraldehyde 3′-phosphate (G3P). Indole is then transferred through a 25-Å hydrophobic tunnel to the β-subunit. The β2 subunit contains pyridoxal 5'-phosphate and catalyzes several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.