Human VEGFB (N-Fc, HEK293)

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Chemical Structure| N/A 同义名 : 重组人VEGFB蛋白(N-Fc, HEK293) ;Recombinant Human VEGFB (N-Fc, HEK293); Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF
CAS号 : N/A
货号 : A2925267
分子式 : -
纯度 : 95% determined by reducing SDS-PAGE.
分子量 : 45.7 KDa
MDL号 : -
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
生物活性
描述 VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance.