Human CEACAM5 (C-Fc, HEK293)
产品说明书
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同义名 : | 重组人CEACAM5蛋白(C-Fc, HEK293) ;Recombinant Human CEACAM5 (C-Fc, HEK293); Carcinoembryonic antigen-related cell adhesion molecule 5; CEACAM5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD66e |
| CAS号 : | N/A | |
| 货号 : | A2925131 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 98.5 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker. | ||