Human MAG (C-6His, HEK293)

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Chemical Structure| N/A 同义名 : 重组人MAG蛋白(C-6His, HEK293) ;Recombinant Human MAG (C-6His, HEK293); Myelin-Associated Glycoprotein; Siglec-4a; MAG; GMA
CAS号 : N/A
货号 : A2924601
分子式 : -
纯度 : 95% determined by reducing SDS-PAGE.
分子量 : 55.7 KDa
MDL号 : -
存储条件:

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
生物活性
描述 Human Myelin-Associated Glycoprotein,also known as MAG, Siglec-4,is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins.MAG contains 4 Ig-like C2-type domains and 1 Ig-like V-type domain.MAG functions as an adhesion molecule during neural development. MAG is believed to be involved in myelination during nerve regeneration. it is a adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells and Preferentially binds to alpha-2,3-linked sialic acid. Soluble MAG, which is released from myelin in large quantities, has been identified in normal human tissues and in tissues from patients with neurological disorders. It is believed that this soluble MAG might contribute to the lack of CNS neuron regeneration after injury.