Human pro-Beta NGF (E.coli)
产品说明书
 |
同义名 : | 重组人pro-Beta NGF蛋白(Tag free, E.coli) ;Recombinant Human pro-Beta NGF (E.coli); Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB; β-NGF; pro-Beta NGF |
| CAS号 : | N/A | |
| 货号 : | A2924130 | |
| 分子式 : | - | |
| 纯度 : | 95% determined by reducing SDS-PAGE. | |
| 分子量 : | 25 KDa | |
| MDL号 : | - | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - |
| 生物活性 | |||
|---|---|---|---|
| 描述 | The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration. | ||