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描述 | 产品名称:Recombinant Human C8 gamma (N-6His)理论分子量:22.6 KDa蛋白种属:Human表达系统:E.coli蛋白表达区间:Gln21-Arg202标签:N-6His剂型:液体纯度:≥95% as determined by SDS-PAGE.储存条件:储存温度≤-70°C,收到后可稳定保存6个月。 储存于≤-70°C,开封后在无菌条件下可稳定保存3个月。 开封后请按照用量分装,尽量减少反复冻融次数。产品背景:Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections. |