Atractylenolide II

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Chemical Structure| 73069-14-4 同义名 : 白术内酯II ;Asterolide; 2-Atractylenolide
CAS号 : 73069-14-4
货号 : A191904
分子式 : C15H20O2
纯度 : 99%
分子量 : 232.32
MDL号 : MFCD09037396
存储条件：

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 105 mg/mL(451.97 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Atractylenolide II is a sesquiterpene compound isolated from the dried rhizome of Atractylodes macrocephala (Baizhu in Chinese) with anti-proliferative activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.30mL

0.86mL

0.43mL

21.52mL

4.30mL

2.15mL

43.04mL

8.61mL

4.30mL
参考文献

[1]Fu XQ, Chou GX, et al. Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II. Exp Dermatol. 2014 Nov;23(11):855-7.

[2]Ye Y, Wang H, et al. Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells. J Ethnopharmacol. 2011 Jun 14;136(1):279-82.