3-Dehydrotrametenolic acid

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Chemical Structure| 29220-16-4 同义名 : 松苓新酸
CAS号 : 29220-16-4
货号 : A1371123
分子式 : C30H46O3
纯度 : 98+%
分子量 : 454.68
MDL号 : MFCD22125011
存储条件：

Pure form Keep in dark place, sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 15 mg/mL(32.99 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO
生物活性
描述 Dehydrotrametenolic acid, a natural product isolated and purified from the roots of Wolfiporia cocos (Schw.) Ryv., can be a potential anticancer agent against H-ras transformed tumor, and is a promising candidate for insulin-sensitizing drug.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.20mL

0.44mL

0.22mL

11.00mL

2.20mL

1.10mL

21.99mL

4.40mL

2.20mL
参考文献

[1]Kang HM, Lee SK, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78(6):607-13.

[2]Sato M, Tai T, et al. Dehydrotrametenolic acid induces preadipocyte differentiation and sensitizes animal models of noninsulin-dependent diabetes mellitus to insulin. Biol Pharm Bull. 2002 Jan;25(1):81-6.