Cetrimonium bromide

产品说明书

Print
Chemical Structure| 57-09-0 同义名 : 十六烷基三甲基溴化铵 ;CTAB; Cetyltrimethylammonium bromide; Hexadecyltrimethylammonium bromide
CAS号 : 57-09-0
货号 : A119034
分子式 : C19H42BrN
纯度 : 98%
分子量 : 364.45
MDL号 : MFCD00011772
存储条件：

Pure form Inert atmosphere, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 :

DMSO: 9 mg/mL(24.69 mM)，配合低频超声助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO

H2O: 4 mg/mL(10.98 mM)，配合低频超声助溶
动物实验配方：
生物活性
描述 Cetrimonium bromide (CTAB), a quaternary ammonium compound, serves as an orally active cationic surfactant. It is recognized for its toxicity and anticancer properties. CTAB modulates cell migration and invasion by influencing both the canonical and non-canonical TGF-β signaling pathways, and it is also employed in DNA extraction processes[1].[2].[3].[4].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.74mL

0.55mL

0.27mL

13.72mL

2.74mL

1.37mL

27.44mL

5.49mL

2.74mL
参考文献

[1]Wu T K, et al. Cetrimonium bromide inhibits cell migration and invasion of human hepatic SK-HEP-1 cells through modulating the canonical and non-canonical TGF-β signaling pathways [J]. Anticancer research, 2019, 39(7): 3621-3631.

[2]Ito E, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer [J]. Molecular pharmacology, 2009, 76(5): 969-983.

[3]Isomaa B, et al. The subacute and chronic toxicity of cetyltrimethylammonium bromide (CTAB), a cationic surfactant, in the rat [J]. Archives of toxicology, 1976, 35: 91-96.

[4]Allen G C, et al. A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide [J]. Nature protocols, 2006, 1(5): 2320-2325.