Y-27632
产品说明书
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同义名 : | - |
| CAS号 : | 146986-50-7 | |
| 货号 : | A112358 | |
| 分子式 : | C14H21N3O | |
| 纯度 : | 99%+ | |
| 分子量 : | 247.34 | |
| MDL号 : | MFCD03093855 | |
| 存储条件： |
Pure form Keep in dark place, sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : |
DMSO: 25 mg/mL(101.08 mM)，配合低频超声，并水浴加热至45℃助溶，注意：DMSO长时间开封后，会吸水并导致溶解能力下降，请避免使用长期开封的DMSO |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Y-27632 is a specific inhibitor of Rho-associated kinases[1]. It is usually used for ES cell maintance[2], cell reprogramming[3],improving cell suviving after thawing[4], as well as facilitates cell proliferation and migration[5]. | ||
| 作用机制 | Y-27632 can inhibit ROCK1 and ROCK2 in an ATP-competition manner.[1] | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.04mL 0.81mL 0.40mL |
20.22mL 4.04mL 2.02mL |
40.43mL 8.09mL 4.04mL |
| 参考文献 |
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